Pulmonary artery pressure and the acute chest syndrome in homozygous sickle cell disease.
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چکیده
منابع مشابه
Pulmonary artery pressure and the acute chest syndrome in homozygous sickle cell disease.
OBJECTIVE To investigate whether attacks of acute chest syndrome affected pulmonary artery pressure in patients homozygous for sickle cell disease. MAIN OUTCOME MEASURES Pulmonary artery pressure, assessed by non-invasive echocardiographic techniques. PATIENTS 20 patients with homozygous sickle cell disease with a history of at least six episodes of acute chest syndrome and in 20 age, sex, ...
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25 consecutive episodes of acute chest syndrome in 13 adult patients with sickle-cell disease were studied retrospectively. Chest symptoms were present on admission in 23 of 25 episodes. Abnormal chest signs and an abnormal chest X-ray were present on admission in only 11 and 9 episodes, respectively, but developed later in the remainder. The 9 episodes with bilateral radiological changes were ...
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The peak expiratory flow rate (PEFR) was studied in 20 matched pairs of children with homozygous sickle cell disease with either no episodes or six or more episodes of acute chest syndrome. The pairs were carefully matched for height and a highly significant reduction in PEFR was observed in children with multiple episodes of acute chest syndrome. Lateral and anteroposterior chest diameters and...
متن کاملPulmonary artery thrombosis during acute chest syndrome in sickle cell disease.
RATIONALE The pathophysiology of acute chest syndrome (ACS) in patients with sickle cell disease is complex, and pulmonary artery thrombosis (PT) may contribute to this complication. OBJECTIVES To evaluate the prevalence of PT during ACS using multidetector computed tomography (MDCT). METHODS We screened 125 consecutive patients during 144 ACS episodes. One hundred twenty-one MDCTs (in 103 ...
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ژورنال
عنوان ژورنال: Heart
سال: 1993
ISSN: 1355-6037
DOI: 10.1136/hrt.69.6.536